Several common dietary and herbal supplements have been linked in medical literature and clinical case studies to cardiovascular strain (including heart attacks or arrhythmias) and severe liver damage or failure:
- Turmeric / Curcumin: High-dose extract supplements (often exceeding 2,000 mg daily) can cause elevated liver enzymes, toxic hepatitis, and liver injury, while some formulations or combinations (like those with black pepper) heighten certain physiological risks. [
- Green Tea Extract: Concentrated doses (particularly EGCG over 800 mg found in weight-loss and energy supplements) are linked to acute liver toxicity/hepatitis, alongside caffeine-induced heart palpitations. [1]
- Niacin (Vitamin B3): Medicinal or high-dose supplemental niacin (often 1,000–5,000 mg/day) can trigger severe liver dysfunction, elevated enzymes, fulminant hepatic failure, and adverse cardiac/metabolic events. [1]
- Yohimbine: A potent nervous system stimulant used for fat loss and performance can cause dangerously high blood pressure, panic attacks, and cardiac arrhythmias. [1]
- Red Yeast Rice: Contains natural statin-like compounds (monacolins) and citrinin that can lead to liver inflammation, myopathy, and kidney or liver stress/failure. [1]
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